Aim: To measure the control of dyslipidemia according to the 2017 AACE guidelines in coronary heart disease (CHD) patients at King Faisal’s Cardiac Center (KFCC) in Jeddah, Saudi Arabia over a period of two years. Methods: Cross-sectional design was employed to collect data of CHD patients from 2016-2018. The inclusion criteria were adults who underwent cardiac catheterization and have received pharmacological therapy for over two months. Exclusion criteria were patients without follow-up lipid profiles. Primary outcome was the percentage of patients who are reaching LDL target; and secondary outcomes included the percentage of patients who are not reaching target whether they were receiving optimum therapy or not, and determine factors associated with increased LDL-C levels. Results: Data was collected for 1413 patients and only 546 patients were included. Using the 2017 AACE guidelines' risk categories, 74.9% of the patients were at extreme risk of cardiovascular complications, with the rest being at very-high risk. Lipid levels post-catheterization showed that only 16.9% of the total population achieved target LDL-C levels. The percentage of patients from the total population that were on optimum therapy and reached target were 15.6%, while17.7% (p-value 0.545) were not on optimum therapy and reached target. When comparing the baseline and post-therapy LDL-C levels there was a mean difference of 0.440 mmol/L decrease in the LDL-C post-therapy level (2-tailed p-value 0.000). The factors significantly associated with patients not reaching the LDL-C target levels were the AACE risk category, age, and diabetes. Conclusion: Our study showed that regardless of optimum lipid lowering therapy, the majority of patients fail to attain lipid targets. More studies should be conducted with the aim of expanding these results and providing better support of evidence on risk factors for CHD and the optimized treatment regimens for patients at KFCC.
Share this page on your timeline