Introduction: Hepatitis is one of the five infectious diseases in the world that yearly one million people die and nearly 2 million sufferers from it. Hepatitis B virus (HBV) is the most important cause of liver disease and the major cause of death from hepatitis in Iran. The purpose of this study was to investigate the knowledge about hepatitis among medical students of Ardabil University of Medical Sciences in 2016. Methodology: This study was a descriptive cross-sectional study that has been done on 150 students were selected randomly from Ardabil University of Medical Sciences students in 2016. The data collected by a questionnaire consisted of 25 questions. The collected data were analyzed using statistical methods in SPSS version 16. P < 5% was considered significant. Results: Of all students, 56% were female, and the rest of them were male with an average age of 20 years. The average of student knowledge was 11.06. Nursing and health students had the highest and IT students had the lowest level of knowledge. 61.3% of students referred to the use of a common syringe as an agent for the transmission of hepatitis and 62% believed that the level of knowledge of people in the community could prevent the transmission of HBV infection to individuals. Conclusion: The results present study showed that students’ knowledge about HBV was moderate and because of medical personnel is at high risk of infection due to their occupational status. Hence, promoting their level of knowledge about HBV is essential.
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