Background: Obesity continues to be a leading public health concern associated with many comorbidities and major hindering effect on the daily lifestyle of many people around the world. Surgical treatment for obesity has proved that it is the best and most effective, durable means of preventing the life-threatening complications and serious problems associated with morbid obesity. Objective: This study aims at identifying the effect of LSG on UGI symptoms after a mean of 6 months of follow up. Patients and Methods: Our study was conducted on 25 morbidly obese patients undergoing LSG for weight reduction. Thorough history, clinical examination and investigations were applied including the validated Rome III Diagnostic questionnaire and UGI endoscopy on cases with sever symptoms. Patients were examined before surgery and had no primary complications. Patients were followed up for 6 months regarding UGI symptoms specially GERD using the same validated Rome III Diagnostic questionnaire. Results: GERD prevalence didn’t significantly change although a significant number of patients recovered from GERD which support the theory that the mechanism of upper GI symptoms after LSG is mainly due to altered motility patterns rather than acid-related disorders. Conclusion: Our results show that LSG represents a safe and effective procedure to achieve significant weight loss. GERD which was considered to be a main troublesome impact of LSG showed no significant change in prevalence, on the contrary appear to abolish the symptom in a significant number of patients who complained of GERD.