Title: Implication of serial coronary CT angiography for prevention of atherosclerotic cardiovascular disease

Abstract

Coronary CT Angiogram was predominantly utilized to detect coronary diameter stenosis for several years. However, with recent advances in techniques to detect atherosclerosis, coronary CT angiograms have been increasingly used to measure plaque burden and further explore plaque characteristics. High-risk plaques, total plaque volume, low-density non-calcified plaques, and calcified plaques are some of the types of plaque characteristics that is now possible to be detected with the help of coronary CT Angiogram. There are numerous clinical trials that have utilized coronary CT angiography to demonstrate the potential benefits of Icosapent ethyl (Vascepa), statins, apixaban, rivaroxaban, aged garlic extract, biologic agents, and omega-3 fatty acids in reducing coronary plaque progression. In addition to the coronary CT Angiogram, a non-contrast cardiac CT scans (calcium scan) can quantify coronary artery calcification (CAC). These calcifications (CAC) are excellent predictors of future cardiac events, and therefore, also provide an opportunity to start preventive therapy like statins and aspirin. In this presentation, I will be discussing the roles of coronary artery calcium scan and coronary CT Angiogram in preventing atherosclerotic cardiovascular disease.