Objective: This study aimed to determine the relationship between one of the most commonly used anesthesia techniques, ketamine-based sedation, on the value of adenoma detection rate (ADR) during colonoscopy screening. Methods: This prospective, observational study included 140 patients, who underwent a standard colonoscopy preparation before the procedure. Sedation regimens included ketamine at 0.5 mg/ kg and propofol at 0.5 mg/kg. Additional doses of propofol were administered at 0.5 mg/kg to maintain the Ramsey Sedation scale. Baseline characteristics, ADR, bowel preparation quality according to the Chicago bowel preparation (CHBP) scale, cecal intubation, colonoscopy removal, and complications were analysed. Results: The mean age of patients was 55.76 years; 40 (28.6%) were males and 100 (71.4%) were females. The ADR was 43.57%, wherein 15.71% in males and 27.86% in females. There were 43.6% adenomas, 17.9% biopsies, and 22.9% polypectomies. The largest location of adenomas/polyps were in the rectum and sigmoid and ascending colon (p=0.11), a biopsy of the sigmoid colon and ileum (p<0.05), polypectomy of the rectum and sigmoid and ascending colon (p<0.05). The cecal intubation was 93.6% with a withdrawal time that is >6 min in most patients (80%) (p<0.05). The CHBP scale showed good bowel preparation (p<0.05) without complications. Conclusions: Ketamine-based sedation is in good overall correlation with ADR. Therefore, the sedation technique should be included for ADR assessment in the future.
Born on October 31, 1988. in Tuzla, Bosnia and Herzegovina. Primary and secondary school finished in Gračanica, Bosnia and Herzegovina. I obtained my medical degree at Faculty of Medicine at the University of Tuzla, and graduated at the same University in 2013. Employed at the Cantonal Hospital Zenica in the Department of Anesthesiology, Resuscitation and Intensive Care since 2013. Anesthesiology residency training started in 2015. Specialist exam passed in 2020. in Tuzla and acquired the title of specialist of anesthesiology, resuscitation and intensive care. My postgraduate (doctoral) studies began in 2019 year at the University of Tuzla. Since then, I have been actively involved in scientific research. As the author and co-author of several published scientific and professional papers. Before and during my doctoral studies, I was a lecturer at numerous domestic and international symposia and congresses, with membership of the Association of Anesthesiologists of the Federation of BiH.
Share this page on your timeline